By: IPP Bureau
Last updated : September 01, 2024 5:01 pm
H.coagulans is, unlike other general lactobacillus, characterized by spore formation, giving it resistance to acid and heat
The Mitsubishi Chemical Group performed a human clinical study of the spore-forming lactic acid producing bacteria probiotic Heyndrickxia coagulans SANK70258 (H. coagulans), and confirmed its effectiveness in decreasing intestinal putrefactive products and intestinal advanced glycation end products (AGEs), as well as improving skin condition. The study results were published in Nutrition on July 25, 2024.
In the intestine, various substances are produced by intestinal bacteria. Phenols, which are produced as intestinal putrefactive products, reportedly reach the skin via the bloodstream to inhibit skin turnover, causing rough skin. AGEs, which result from proteins and sugars heated by body temperature in the intestine, are believed to cause skin aging by circulating and accumulating throughout the body.
Therefore, improving the intestinal environment is believed to lead to maintaining a healthy skin condition and preventing rough skin.
H.coagulans is, unlike other general lactobacillus, characterized by spore formation, giving it resistance to acid and heat. This allows it to survive the journey to the intestine, where it can germinate and proliferate. Previously, we have confirmed its functionalities including improvement of bowel movements and regulation of immune functions. We conducted a human clinical study to verify the functionality of H. coagulans in improving the intestinal environment and skin condition. The study involved 80 Japanese women aged 30 to 65 who received a capsule containing at least 1 billion cells of H. coagulans.
These findings suggest that intake of H. coagulans may improve the intestinal environment, brighten skin tone, and maintain healthy skin, by affecting intestinal microbiota.