This alliance, covering up to 12 antibody drugs, highlights the growing trend of large-scale collaborations between Chinese biotech firms and global pharmaceutical giants
The JADE trial enrolled 164 U.S. patients who initially received three monthly doses of OLN324 or faricimab, followed by 12 weeks off treatment with retreatment allowed only if disease recurred
Takeda will pay Innovent US$1.2 billion upfront, including a US$100 million equity investment in Innovent
Innovent plans to soon submit a new drug application (NDA) to China’s National Medical Products Administration
Takeda will make an upfront payment of $1.2 billion, which includes a $100 million equity investment in Innovent
Mankind Pharma will have exclusive rights to register, import, market, sell and distribute sintilimab in India
Innovent will supply sintilimab for the collaborated clinical trial
LG Chem will receive totaling up to $95.5 million for the China rights
The NMPA Breakthrough Therapy Designation was based on results from the Phase 2 TRUST trial of ROS1 fusion-positive NSCLC patients treated with taletrectinib, a new generation of potent ROS1 inhibitors
DME is among the most challenging retinal diseases to treat and has long served as a proving ground for therapies that ultimately become first-line standard of care in retinal diseases
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