The LIFT-PD study will enroll 75 Parkinson’s patients experiencing apathy across 16 sites in Germany, Bulgaria, Poland and Spain
The move follows encouraging Phase I data and a series of regulatory wins from the U.S. Food and Drug Administration
The upcoming Phase I trial will test the safety, tolerability, and pharmacokinetics of ISM8969 in healthy volunteers and determine the optimal dosing for future studies
The Phase 1 single and multiple ascending dose study is set to begin dosing in early Q1 2026
The mPTP plays a key role in mitochondrial dysfunction, inflammation, and neuronal death in neurodegenerative diseases
Ventyx's clinical pipeline includes multiple small molecules with potential for oral therapies addressing chronic inflammation
Applications include detailed scientific rationale and supporting clinical evidence
The multicenter study will enroll 75 patients across 16 sites in Germany, Bulgaria, Poland, and Spain
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