Lilly's tirzepatide delivered up to 22.5% weight loss in adults with obesity
Participants taking tirzepatide lost up to 52 lb. (24 kg) in this 72-week phase 3 study
Participants taking tirzepatide lost up to 52 lb. (24 kg) in this 72-week phase 3 study
Approval is based on results from the phase 3 OASIS 4 clinical trial
The company said data from multiple VESPER studies show the peptide delivered meaningful weight loss, favorable tolerability, and the possibility of a first-in-class monthly injection format
The company said Wegovy hit its first one million prescriptions within 12 weeks of availability
The results come from post-hoc analyses of more than 1,500 women enrolled in the Phase 3 ATTAIN-1 and ATTAIN-2 trials, presented at the American Diabetes Association’s 86th Scientific Sessions
Based on the cumulative data from ACHIEVE-1 through ACHIEVE-5, Lilly plans to submit orforglipron for FDA approval for the treatment of type 2 diabetes by the end of the second quarter
The move signals a major expansion in access to next-generation weight-loss therapies
The company is set to unveil new clinical data across obesity, diabetes, kidney, and liver disease programs
The company said all doses achieved statistically significant reductions in body weight compared with placebo at 72 weeks
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