Microbion Corporation announced that the US Patent and Trademark Office (USPTO) issued United States Patent No. 11,464,749 to Microbion with claims to the use of Microbion's proprietary pravibismane inhaled composition for treatment of pulmonary infections.

The patent, entitled "Bismuth-thiol compositions and methods of use," extends inhaled pravibismane patent protection through mid-2039. The granted claims cover the administration and use of inhaled pravibismane compositions in pulmonary infections. This patent further expands Microbion's patent portfolio, comprising granted claims to its pravibismane composition and methods of treating infections of the respiratory tract.

"We are pleased that this new patent supporting our inhaled pravibismane program has been granted by the USPTO," said Karim Lalji, CEO of Microbion Pharma Corp. "This patent is a culmination of many years of work and strengthens our patent position to develop inhaled pravibismane as a potential viable treatment option that addresses several unmet needs for patients living with debilitating lung infection. Having successfully completed GLP toxicology studies, we are excited to be advancing our inhaled development program towards first in human studies."

Inhaled pravibismane has received QIDP, Fast Track and Orphan drug designation from the US FDA for the treatment (management) of pulmonary infections in patients with cystic fibrosis. Microbion has successfully completed non-clinical studies for the inhaled pravibismane program and is preparing for initiation of clinical trials.