ProBioGen’s vaccine production cell line AGE1.CR.pIX used for clinical production
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ProBioGen’s vaccine production cell line AGE1.CR.pIX used for clinical production

The AGE1.CR.pIX cell line is derived from primary cells of a duck embryo and was designed to comply with health authority guidelines

  • By IPP Bureau | January 20, 2023

ProBioGen is announcing another important clinical milestone for its proprietary viral vector and vaccine production cell line AGE1.CRpIX®. Our valued customer Nouscom recently proclaimed that their sub-licensee, has initiated phase 1 clinical trials for VAC85135, a viral vector-based cancer vaccine for an oncologic indication. The MVA-based component of the vaccine was produced using ProBioGen's AGE1.CR.pIX. 

The AGE1.CR.pIX cell line is derived from primary cells of a duck embryo and was designed to comply with health authority guidelines and the concept of "defined risk". It was developed as an alternative to the use of chicken eggs for large-scale vaccine production.

The AGE1.CR.pIX cell line grows in true suspension and has been optimized for viral vaccine production and stability. It grows in a commercially available, chemically defined medium without animal components and is an excellent host for a variety of different virus strains.

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