NCFB is a chronic lung condition where damaged airways cause persistent coughing and mucus production
The development marks an important step in Sigachi's strategic focus on expanding its presence in complex, high-value specialty APIs, aligned with global demand for advanced therapies in rare and chronic disease segments
The study found that nerandomilast effectively slowed lung function decline in patients, with discontinuation rates similar to placebo
Enzomenib, an oral, small-molecule inhibitor designed to disrupt the menin-MLL protein interaction involved in leukemogenesis
New data on the secondary endpoint shows up to 52.3% of adults with fibrosis stages F1, F2 and F3 had improvement in fibrosis due to MASH
Commercial terms include research funding and milestones and/or royalty payments to Evotec based on the success of the program
Decision on EU marketing authorisation expected for momelotinib by early 2024
Approval is for use in myelofibrosis patients with anaemia regardless of prior myelofibrosis therapy
48-week data from MOMENTUM phase III clinical trial show momelotinib maintained total symptom response
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