Merck announced the start of construction for a $3 billion, 400,000-square-foot pharmaceutical manufacturing facility at its Elkton, Virginia, site.

Merck’s investment in the Center of Excellence for pPharmaceutical manufacturing is part of a more than $70 billion investment beginning in 2025 to expand domestic manufacturing and research and development — not including any future business development transactions in R&D — to drive its long-term growth and strengthen the status of the U.S. as a global leader in biopharmaceutical innovation. 

“Today is an important milestone for Merck, for Virginia, for manufacturing in the United States and, most importantly, for the patients we serve,” said Robert M. Davis, chairman and chief executive officer, Merck. “This investment helps advance our goal of providing new, innovative treatment options for people facing serious health challenges in the U.S. and around the world.”

The $3 billion expansion c builds on Merck’s nearly 85-year history in Elkton, Virginia, enhancing the site with a state-of-the-art pharmaceutical Center of Excellence that will include both Active Pharmaceutical Ingredient and Drug Product investment supporting small molecule manufacturing and testing and will potentially create more than 500 full-time roles as well as 8,000 construction jobs.

“Merck’s transformational $3 billion commitment to locate its Center of Excellence marks a giant leap forward for both America’s and Virginia’s life sciences sector,” said Gov. Glenn Youngkin. “It deepens the company’s long-standing commitment to innovation and strengthens the Commonwealth’s position as the emerging national leader in biopharmaceutical advanced manufacturing and life sciences. With hundreds of new jobs and cutting-edge capabilities coming to the Shenandoah Valley, we’re building a future where Virginians lead the way in developing lifesaving medicines for patients around the world.”

This year alone, Merck has announced nearly $6 billion in manufacturing investments across North Carolina, Delaware, Kansas and Virginia that are anticipated to create more than 1,600 new American jobs.